Here is a list of the must-know topics for USMLE® Step 1—handpicked by our expert physicians and analytics team. These show up on almost every exam form, so skipping them isn’t the smartest move.
Bookmark this page to find a collection of handy links directly to the proven AMBOSS content covering all these topics.
Make sure you master these before your exam to ensure a higher score.
Each of the 50 topics can be found within the AMBOSS Knowledge Library and Qbank. To access them, you need to create an AMBOSS account if you haven’t already.
1. Bookmark this page and study at your own pace—return after each topic to stay on track and maximize your score.
Additional Study Tips:
2. Test yourself as often as you can. The grey arrow at the top of each Article leads to a USMLE®-style Qbank session covering all the tested concepts from the topic you’re reviewing.
3. Take advantage of features like High-Yield Mode, Highlighting, pop-up definitions and more, which will help you pick out key points quickly and condense your study time.
4. Add your own personal notes to the Articles to build upon your knowledge and keep all your learnings in one place.
5. Gain valuable insights through our blog-posts that will give you an added push towards your goal:
All packages include access to the library, Qbank, study plans, Anki integration, score predictor, and clinical tools for the duration of the membership.
$378
(Billed yearly)
$448
(Billed yearly)
$1199
*From now until end of PGY-1
Forward your receipt of payment to refund@amboss.com within 30 days of purchasing. We will cancel your membership and return you the full amount, no questions asked. Refunds are given only to purchases made directly through AMBOSS.
All these topics, study plans, and content reviews for every Step exam are included in your AMBOSS access
© 2025 AMBOSS. All rights reserved.
The United States Medical Licensing Examination (USMLE®️) is a joint program of the Federation of State Medical Boards (FSMB®️) and the National Board of Medical Examiners (NBME®️). The Comprehensive Osteopathic Medical Licensing Examination (COMLEX-USA®️) is administered by the National Board of Osteopathic Medical Examiners (NBOME®️). Additionally, the National Commission on Certification of Physician Assistants (NCCPA®️) governs the Physician Assistant National Certifying Exam (PANCE®️) and related certifications. ABIM®️ is a registered trademark of the American Board of Internal Medicine. ABFM®️ is a registered trademark of the American Board of Family Medicine. None of the trademark holders mentioned are affiliated with AMBOSS.
